Veterinary Surgical Centers

Portosystemic Shunt

What is a Portosystemic Shunt?

Normally, the blood supply draining the intestines travels through the portal vein into the liver where it is filtered, then returns to the heart via the caudal vena cava. A portosystemic shunt (PSS) is an abnormal vein connecting the blood supply returning from the intestines to the vein returning blood to the heart, bypassing the liver (shunting). Portosystemic shunts can be either congenital (present at birth) or acquired. Acquired PSS can develop in pets that have progressive liver dysfunction. Congenital PSS can be found within the liver (intrahepatic) or before the liver (extrahepatic). Intrahepatic shunts are more commonly found in large-breed dogs such as German shepherds, Labrador retrievers, golden retrievers, Irish Setters, Doberman Pinschers, and Irish Wolfhounds. Extrahepatic shunts are more commonly found in miniature and toy breed dogs such as Yorkshire terriers, miniature schnauzers, poodles, Lhasa apsos, and Pekingese as well as cats.

What are the symptoms?

A patient with a PSS can show symptoms such as poor weight gain, increased thirst and urination, increased salivation (more common in cats), vomiting, diarrhea, straining or difficulty urinating due to bladder stone development, and neurological symptoms such as dementia, circling, blindness and seizures. Occasionally, no symptoms are seen at all and the animal may be the 'runt' of the litter.

What are the goals of surgery - Extrahepatic PSS?

Abdominal surgery is common and considered the treatment of choice for extrahepatic PSS. At surgery our goal is to locate and place an ameroid constrictor around the blood vessel to allow gradual occlusion. An ameroid constrictor is a stainless steel ring surrounding a casein center. Casein is a material that will gradually swell in the body fluids, allowing slow occlusion of the shunt. Gradual occlusion allows the liver to adapt to the increased blood flow. In rare instances, the PSS can be completely ligated (tied-off) at the time of surgery.

What are the goals of surgery - Intrahepatic PSS?

Although an intrahepatic shunt can be addressed as an abdominal surgery, the risks and complications during and after surgery are higher. Exposing these shunts may require dissection into the liver and they tend to be larger, making it more difficult to occlude. Therefore, newer procedures have been developed to allow occlusion of the shunt through minimally invasive techniques with the aid of catheters and interventional radiology. Most of these procedures are currently being performed at academic institutions such as the University of Pennsylvania.

What is the surgical outcome?

Based on the current literature, and in our experience, 80% of dogs with an extrahepatic PSS will have an excellent outcome. About 10% of dogs will have a recurrence of signs and will require continued medical management. About 7% of dogs will have severe problems such as seizures or other systemic problems after surgery that may result in death.